MIDN and MAP3K20

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		MIDN	MAP3K20
Description		midnolin	mitogen-activated protein kinase kinase kinase 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding Kinase Binding	Magnesium Ion Binding RNA Binding MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Biological_process Negative Regulation Of Glucokinase Activity Negative Regulation Of Insulin Secretion	DNA Damage Checkpoint Signaling Protein Phosphorylation Cytoskeleton Organization Cell Cycle JNK Cascade Cell Death Cell Differentiation P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Regulation Of Cell Cycle Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint
Pathways
Drugs			Dasatinib Fostamatinib
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Haemorrhoidal disease ( 33888516)
Interacting Genes		9 interacting genes: CMTM4 GADD45A GADD45G KRT34 MAP3K20 PLEKHF2 SYNGR3 TRIM55 TRIM63	32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775
Entrez ID		90007	51776
HPRD ID		16230	11791
Ensembl ID		ENSG00000167470	ENSG00000091436
Uniprot IDs		Q504T8	D4Q8H0 Q9NYL2
PDB IDs			5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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