MAP3K20 and ZNF593

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		MAP3K20	ZNF593
Description		mitogen-activated protein kinase kinase kinase 20	zinc finger protein 593
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleoplasm Nucleolus
	Molecular Function	Magnesium Ion Binding RNA Binding MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	DNA Damage Checkpoint Signaling Protein Phosphorylation Cytoskeleton Organization Cell Cycle JNK Cascade Cell Death Cell Differentiation P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Regulation Of Cell Cycle Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint	Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
Drugs		Dasatinib Fostamatinib
Diseases
GWAS		Haemorrhoidal disease ( 33888516)
Interacting Genes		32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775	11 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 PIGV POLR1H RAB1A SRPK2
Entrez ID		51776	51042
HPRD ID		11791	15866
Ensembl ID		ENSG00000091436	ENSG00000142684
Uniprot IDs		D4Q8H0 Q9NYL2	O00488
PDB IDs		5HES 5X5O 6JUT 6JUU	1ZR9 6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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