MAP3K20 and ZNF775

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		MAP3K20	ZNF775
Description		mitogen-activated protein kinase kinase kinase 20	zinc finger protein 775
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus
	Molecular Function	Magnesium Ion Binding RNA Binding MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	DNA Damage Checkpoint Signaling Protein Phosphorylation Cytoskeleton Organization Cell Cycle JNK Cascade Cell Death Cell Differentiation P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Regulation Of Cell Cycle Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs		Dasatinib Fostamatinib
Diseases
GWAS		Haemorrhoidal disease ( 33888516)	Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775	18 interacting genes: CARD10 CEP70 CYSRT1 DVL3 EHMT2 FAM9A FES KRTAP10-8 MAP3K20 MAPK6 MTUS2 OSGEP PPP2CB RPS6KA5 TRIM55 TRIM63 TSPYL2 ZRANB1
Entrez ID		51776	285971
HPRD ID		11791	14567
Ensembl ID		ENSG00000091436	ENSG00000196456
Uniprot IDs		D4Q8H0 Q9NYL2	Q96BV0
PDB IDs		5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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