GPAA1 and GIT1

		GPAA1	GIT1
Description		glycosylphosphatidylinositol anchor attachment 1	GIT ArfGAP 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Mitochondrion Centrosome Cytosol Focal Adhesion Postsynaptic Density Membrane Lamellipodium Calyx Of Held Mitotic Spindle Pole Postsynapse
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	GTPase Activator Activity Protein Binding Gamma-tubulin Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	Intramembranous Ossification Brain Development Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Negative Regulation Of Interleukin-1 Beta Production Cell Redox Homeostasis Negative Regulation Of Glycolytic Process Ephrin Receptor Signaling Pathway Neuron Development Regulation Of Catalytic Activity Motor Learning Cellular Response To Lipopolysaccharide Positive Regulation Of Microtubule Nucleation Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Inflammatory Response To Wounding Regulation Of Synaptic Vesicle Exocytosis
Pathways		Attachment of GPI anchor to uPAR	Ephrin signaling Ephrin signaling CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)	Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL	54 interacting genes: ARHGEF6 ARHGEF7 B9D1 BARD1 C8orf33 CCDC113 CDC42 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GPAA1 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG
Entrez ID		8733	28964
HPRD ID		04334	06577
Ensembl ID		ENSG00000197858	ENSG00000108262
Uniprot IDs		O43292	Q59FC3 Q9Y2X7
PDB IDs
Enriched GO Terms of Interacting Partners?
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