GPAA1 and NDRG1

		GPAA1	NDRG1
Description		glycosylphosphatidylinositol anchor attachment 1	N-myc downstream regulated 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Nucleus Cytoplasm Centrosome Cytosol Microtubule Plasma Membrane Adherens Junction Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Glutamatergic Synapse
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	Protein Binding Microtubule Binding Small GTPase Binding Gamma-tubulin Binding Cadherin Binding
	Biological Process	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Mast Cell Activation Cellular Response To Hypoxia Postsynapse Organization
Pathways		Attachment of GPI anchor to uPAR	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Drugs
Diseases
GWAS		Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)	Estimated glomerular filtration rate ( 31015462) Left-handedness ( 32989287) Nontyphoidal Salmonella bacteraemia ( 29523850) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes		19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL	72 interacting genes: ACSL3 ACTG1 AP1M2 AP2M1 APOA1 APOA2 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E EWSR1 FASN GPAA1 GSK3B HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME MYC NCL NR4A1 PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RTN1 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS1 TFAP2B TLE3 UPF1 VCP XRCC5 ZNF155
Entrez ID		8733	10397
HPRD ID		04334	05586
Ensembl ID		ENSG00000197858	ENSG00000104419
Uniprot IDs		O43292	B3KWB2 Q8N959 Q92597
PDB IDs			6ZMM
Enriched GO Terms of Interacting Partners?
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