GPAA1 and CACNG8

		GPAA1	CACNG8
Description		glycosylphosphatidylinositol anchor attachment 1	calcium voltage-gated channel auxiliary subunit gamma 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Plasma Membrane Voltage-gated Calcium Channel Complex Postsynaptic Density Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Postsynaptic Density Membrane L-type Voltage-gated Calcium Channel Complex
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Channel Regulator Activity
	Biological Process	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	Calcium Ion Transport Transmission Of Nerve Impulse Positive Regulation Of Synaptic Transmission, Glutamatergic Calcium Ion Transmembrane Transport Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Postsynaptic Neurotransmitter Receptor Diffusion Trapping Neurotransmitter Receptor Internalization Regulation Of AMPA Receptor Activity
Pathways		Attachment of GPI anchor to uPAR	Trafficking of AMPA receptors Phase 0 - rapid depolarisation Phase 2 - plateau phase LGI-ADAM interactions
Drugs			Ergocalciferol Enflurane Spironolactone Butamben Bioallethrin
Diseases
GWAS		Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)
Interacting Genes		19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL	1 interacting genes: GPAA1
Entrez ID		8733	59283
HPRD ID		04334	06063
Ensembl ID		ENSG00000197858	ENSG00000142408
Uniprot IDs		O43292	Q8WXS5
PDB IDs
Enriched GO Terms of Interacting Partners?
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