TRAF7 and HDGF

		TRAF7	HDGF
Description		TNF receptor associated factor 7	heparin binding growth factor
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Transcription Repressor Complex Collagen-containing Extracellular Matrix
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Nucleotide Binding Transcription Corepressor Binding Double-stranded DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity RNA Binding Growth Factor Activity Heparin Binding
	Biological Process	Ribosomal Large Subunit Assembly Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Signal Transduction Cellular Response To Interleukin-7
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	XBP1(S) activates chaperone genes
Drugs			Copper
Diseases
GWAS		Diastolic blood pressure ( 30578418) Height ( 28552196) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Blood protein levels ( 30072576) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: BTBD1 CDC42 CYLD HAGHL HDGF MAP3K3 NUDT16L1 OGT PBXIP1 PPIC RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6	6 interacting genes: APP GPR37 JUN SMAD4 TRAF7 XBP1
Entrez ID		84231	3068
HPRD ID		06977	02079
Ensembl ID		ENSG00000131653	ENSG00000143321
Uniprot IDs		B3KQY7 Q6Q0C0	A0A384NPW1 A8K8G0 B7Z958 P51858
PDB IDs			1RI0 2NLU
Enriched GO Terms of Interacting Partners?
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