TRAF7 and PBXIP1

		TRAF7	PBXIP1
Description		TNF receptor associated factor 7	PBX homeobox interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Chromatin Nucleus Transcription Regulator Complex Cytosol Microtubule Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding
	Biological Process	Ribosomal Large Subunit Assembly Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway	Production Of Molecular Mediator Involved In Inflammatory Response Cell Adhesion Multicellular Organism Development Cell Migration Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Articular Cartilage Development Histone H3-K56 Acetylation Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Height ( 28552196) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		18 interacting genes: BTBD1 CDC42 CYLD HAGHL HDGF MAP3K3 NUDT16L1 OGT PBXIP1 PPIC RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6	28 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TRAF7 TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		84231	57326
HPRD ID		06977	17823
Ensembl ID		ENSG00000131653	ENSG00000163346
Uniprot IDs		B3KQY7 Q6Q0C0	B4E0K4 Q96AQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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