KBTBD7 and NFKBIE

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

		KBTBD7	NFKBIE
Description		kelch repeat and BTB domain containing 7	NFKB inhibitor epsilon
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cul3-RING Ubiquitin Ligase Complex	Fibrillar Center Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Signal Transduction Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Cytoplasmic Sequestering Of Transcription Factor
Pathways		Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Activation of NF-kappaB in B cells
Drugs
Diseases
GWAS			Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Rheumatoid arthritis ( 32723749 30423114 22446963 23028356 24390342)
Interacting Genes		19 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3	21 interacting genes: ANKHD1 BYSL C1QBP COG7 CUL1 GUCA1B HDAC4 HDAC5 IL1A JUP KBTBD7 NCOR2 NFKB1 NFKB2 NPR3 PEX6 POLH PPP6C REL RELA SKP1
Entrez ID		84078	4794
HPRD ID		13759	05181
Ensembl ID		ENSG00000120696	ENSG00000146232
Uniprot IDs		Q8WVZ9	A0A024RD24 O00221 Q7LC14 Q96F31
PDB IDs
Enriched GO Terms of Interacting Partners?
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