KBTBD7 and DUSP23

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		KBTBD7	DUSP23
Description		kelch repeat and BTB domain containing 7	dual specificity phosphatase 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Negative Regulation Of Signal Transduction Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			4-Nitrophenyl Phosphate
Diseases
GWAS			Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		19 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3	32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746
Entrez ID		84078	54935
HPRD ID		13759	07908
Ensembl ID		ENSG00000120696	ENSG00000158716
Uniprot IDs		Q8WVZ9	A0A140VJI5 Q9BVJ7
PDB IDs			2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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