NFKBIE and BYSL

		NFKBIE	BYSL
Description		NFKB inhibitor epsilon	bystin like
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Cytoplasmic Sequestering Of Transcription Factor	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Population Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Activation of NF-kappaB in B cells	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Rheumatoid arthritis ( 32723749 30423114 22446963 23028356 24390342)	Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 20139978)
Interacting Genes		21 interacting genes: ANKHD1 BYSL C1QBP COG7 CUL1 GUCA1B HDAC4 HDAC5 IL1A JUP KBTBD7 NCOR2 NFKB1 NFKB2 NPR3 PEX6 POLH PPP6C REL RELA SKP1	144 interacting genes: AIMP2 AMOTL2 APP ATP5F1B AXIN2 BEND7 BFSP1 BHLHE40 C1orf94 CAVIN4 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EAPP EMD EPS8 ETF1 FAM228A FAM9B FCHO1 FXR1 FXR2 GAS8 GMCL1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 JRK KATNAL1 KIFC3 KLHL2 KLHL6 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LDOC1 LHX3 LMNA LMO1 LMO2 LONRF1 LTV1 LZTS1 LZTS2 MB21D2 MCIDAS MEOX1 MEOX2 MID1 MID2 MIPOL1 MKRN1 MRFAP1L1 MTUS2 NECAB2 NF2 NFKBIE OGT OLIG3 OSBPL3 PDE4DIP PHC2 PICK1 PIH1D1 PNMA1 PNMA2 PRICKLE1 PSMC6 PTK7 RACGAP1 RACK1 RALY RALYL RBAK RGS4 RP9 RUBCN SMN1 SMN2 SNW1 SSX2IP STX11 TBC1D26 TEKT1 TFIP11 THAP1 TLE5 TNIP1 TRAF2 TRAF4 TRAK1 TRIM14 TRIM27 TRIM37 TRIM38 TRIM41 TRIM54 TRIM55 TRIP6 TRO TROAP UBE2H USH1G VIM VPS37B VPS52 WASF3 WTAP ZBTB14 ZBTB8A ZC2HC1C ZFP64 ZMAT5 ZNF212 ZNF286A ZNF426 ZNF438 ZNF48 ZNF655 ZNF668 ZNF71 ZNF835 ZRANB1 ZSCAN22
Entrez ID		4794	705
HPRD ID		05181	04848
Ensembl ID		ENSG00000146232	ENSG00000112578
Uniprot IDs		A0A024RD24 O00221 Q7LC14 Q96F31	Q13895
PDB IDs			6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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