KBTBD7 and KLF15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KBTBD7	KLF15
Description		kelch repeat and BTB domain containing 7	Kruppel like factor 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cul3-RING Ubiquitin Ligase Complex	Chromatin Nucleus Nucleoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Signal Transduction Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Cellular Glucose Homeostasis Regulation Of Transcription By RNA Polymerase II Glial Cell Differentiation Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Wnt Signaling Pathway Response To Insulin Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Glomerular Visceral Epithelial Cell Differentiation Cellular Response To Peptide Negative Regulation Of Peptidyl-lysine Acetylation
Pathways		Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation	BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS			Macular telangiectasia type 2 ( 28250457) Male-pattern baldness ( 28196072) Manganese levels ( 26025379) Metabolite levels ( 23378610) Refractive error ( 32231278) Urate levels ( 31578528)
Interacting Genes		19 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3	24 interacting genes: ANKS1A APPL1 BANP C11orf68 C1orf109 CCDC57 CRK DVL3 HNRNPF KBTBD7 NFYC NRF1 PIK3R3 POLR1C PRKAB2 SCNM1 SHFL SNX13 STAT3 SUV39H1 TCF21 ZBTB24 ZNF330 ZNF76
Entrez ID		84078	28999
HPRD ID		13759	07568
Ensembl ID		ENSG00000120696	ENSG00000163884
Uniprot IDs		Q8WVZ9	Q9UIH9
PDB IDs			2ENT
Enriched GO Terms of Interacting Partners?
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