SPOP and GMEB1

Number of citations of the paper that reports this interaction (PubMedID 28805822)
78

Data Source:
BioGRID (two hybrid)

		SPOP	GMEB1
Description		speckle type BTB/POZ protein	glucocorticoid modulatory element binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Basophil count ( 32888494)
Interacting Genes		68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	16 interacting genes: ARID1A ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		8405	10691
HPRD ID		16004	16059
Ensembl ID		ENSG00000121067	ENSG00000162419
Uniprot IDs		O43791	B1AT47 B2RCN8 Q9Y692
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D	1OQJ
Enriched GO Terms of Interacting Partners?
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