SPOP and RTN3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPOP	RTN3
Description		speckle type BTB/POZ protein	reticulon 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Apoptotic Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation
Pathways		Hedgehog 'on' state	Synaptic adhesion-like molecules
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	32 interacting genes: AGTR1 AKAP8 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SHANK3 SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391
Entrez ID		8405	10313
HPRD ID		16004	18516
Ensembl ID		ENSG00000121067	ENSG00000133318
Uniprot IDs		O43791	A0A024R5C4 O95197
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D	7BRU
Enriched GO Terms of Interacting Partners?
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