RPS6KL1 and NEK9

		RPS6KL1	NEK9
Description		ribosomal protein S6 kinase like 1	NIMA related kinase 9
Image		No pdb structure
GO Annotations	Cellular Component	Ribosome	Nucleus Centrosome Cytosol
	Molecular Function	ATP Binding Protein Serine Kinase Activity	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation	Protein Phosphorylation Cell Cycle Cell Division
Pathways			Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) HDL cholesterol levels ( 32203549) Mood instability ( 29187730) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		5 interacting genes: BBOF1 CIPC LIN52 MIDEAS NEK9	21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33
Entrez ID		83694	91754
HPRD ID		18004	11386
Ensembl ID		ENSG00000198208	ENSG00000119638
Uniprot IDs		B4DSP6 Q9Y6S9	A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19
PDB IDs			3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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