TRIM7 and CFL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM7	CFL2
Description		tripartite motif containing 7	cofilin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Actin Filament Binding
	Biological Process	Protein Ubiquitination	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing
Pathways
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Takayasu arteritis ( 33308445)
Interacting Genes		27 interacting genes: AQP1 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RSPH14 RWDD2B SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1	15 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LAIR1 LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I ZYG11B
Entrez ID		81786	1073
HPRD ID		11648	03262
Ensembl ID		ENSG00000146054	ENSG00000165410
Uniprot IDs		Q9C029	Q549N0 Q9Y281
PDB IDs
Enriched GO Terms of Interacting Partners?
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