CFL2 and DSTN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CFL2	DSTN
Description		cofilin 2	destrin, actin depolymerizing factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome	Cytoplasm Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding Actin Filament Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Cell Motility Actin Filament Severing
Pathways
Drugs			Dodecyldimethylamine N-oxide
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Takayasu arteritis ( 33308445)	Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)
Interacting Genes		15 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LAIR1 LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I ZYG11B	8 interacting genes: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2
Entrez ID		1073	11034
HPRD ID		03262	16446
Ensembl ID		ENSG00000165410	ENSG00000125868
Uniprot IDs		Q549N0 Q9Y281	P60981 V9HWA6
PDB IDs
Enriched GO Terms of Interacting Partners?
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