CFL2 and CAP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CFL2	CAP2
Description		cofilin 2	cyclase associated actin cytoskeleton regulatory protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome	Cytoplasm Plasma Membrane Postsynaptic Density
	Molecular Function	Protein Binding Actin Filament Binding	Actin Binding Protein Binding Adenylate Cyclase Binding Identical Protein Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing	Cell Morphogenesis Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity CAMP-mediated Signaling Regulation Of Adenylate Cyclase Activity
Pathways			Role of ABL in ROBO-SLIT signaling
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Takayasu arteritis ( 33308445)	Haemorrhoidal disease ( 33888516) Height ( 18391951) Mitochondrial DNA levels ( 25240745) QT interval ( 29213071) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		15 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LAIR1 LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I ZYG11B	10 interacting genes: ACTG1 ADO ALAS1 CAP1 CFL2 DTNBP1 GRXCR1 MT1P3 PRPF40A YWHAE
Entrez ID		1073	10486
HPRD ID		03262	10808
Ensembl ID		ENSG00000165410	ENSG00000112186
Uniprot IDs		Q549N0 Q9Y281	P40123 Q5JPJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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