RMI1 and HSPA13

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RMI1	HSPA13
Description		RecQ mediated genome instability 1	heat shock protein family A (Hsp70) member 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body RecQ Family Helicase-topoisomerase III Complex	Cytoplasm Mitochondrion Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding	Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Via Homologous Recombination DNA Replication	Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding
Pathways		HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	Regulation of HSF1-mediated heat shock response
Drugs			Copper
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Childhood body mass index ( 33045005) Hip circumference adjusted for BMI ( 34021172) Menarche (age at onset) ( 27182965 25231870) Molar-incisor hypomineralization ( 23918034) Response to statin therapy ( 20339536) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking status (ever vs never smokers) ( 30643258) Triglycerides ( 30275531)
Interacting Genes		5 interacting genes: FANCM HSPA13 NR1H2 PFDN1 UBE3A	11 interacting genes: BAG6 CRYGA OGT POLE4 RMI1 SGTA SGTB SSR1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		80010	6782
HPRD ID		09867	03061
Ensembl ID		ENSG00000178966	ENSG00000155304
Uniprot IDs		Q9H9A7	A0A140VK72 P48723
PDB IDs		3MXN 3NBH 3NBI 4CGY 4CHT 4DAY
Enriched GO Terms of Interacting Partners?
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