HSPA13 and RMI1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		HSPA13	RMI1
Description		heat shock protein family A (Hsp70) member 13	RecQ mediated genome instability 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleoplasm Nuclear Body RecQ Family Helicase-topoisomerase III Complex
	Molecular Function	Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	Nucleotide Binding Protein Binding
	Biological Process	Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Via Homologous Recombination DNA Replication
Pathways		Regulation of HSF1-mediated heat shock response	HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs		Copper
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Childhood body mass index ( 33045005) Hip circumference adjusted for BMI ( 34021172) Menarche (age at onset) ( 27182965 25231870) Molar-incisor hypomineralization ( 23918034) Response to statin therapy ( 20339536) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking status (ever vs never smokers) ( 30643258) Triglycerides ( 30275531)
Interacting Genes		11 interacting genes: BAG6 CRYGA OGT POLE4 RMI1 SGTA SGTB SSR1 UBQLN1 UBQLN2 UBQLN4	5 interacting genes: FANCM HSPA13 NR1H2 PFDN1 UBE3A
Entrez ID		6782	80010
HPRD ID		03061	09867
Ensembl ID		ENSG00000155304	ENSG00000178966
Uniprot IDs		A0A140VK72 P48723	Q9H9A7
PDB IDs			3MXN 3NBH 3NBI 4CGY 4CHT 4DAY
Enriched GO Terms of Interacting Partners?
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