RMI1

Description		RecQ mediated genome instability 1
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GO Annotations	Cellular Component	Nucleoplasm Nuclear Body RecQ Family Helicase-topoisomerase III Complex
	Molecular Function	Nucleotide Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Via Homologous Recombination DNA Replication
Pathways		HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Childhood body mass index ( 33045005) Hip circumference adjusted for BMI ( 34021172) Menarche (age at onset) ( 27182965 25231870) Molar-incisor hypomineralization ( 23918034) Response to statin therapy ( 20339536) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking status (ever vs never smokers) ( 30643258) Triglycerides ( 30275531)
Interacting Genes		5 interacting genes: FANCM HSPA13 NR1H2 PFDN1 UBE3A
Entrez ID		80010
HPRD ID		09867
Ensembl ID		ENSG00000178966
Uniprot IDs		Q9H9A7
PDB IDs		3MXN 3NBH 3NBI 4CGY 4CHT 4DAY
Enriched GO Terms of Interacting Partners?
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