RMI1 and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RMI1	PFDN1
Description		RecQ mediated genome instability 1	prefoldin subunit 1
Image
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body RecQ Family Helicase-topoisomerase III Complex	Cytoplasm Prefoldin Complex
	Molecular Function	Nucleotide Binding Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Via Homologous Recombination DNA Replication	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways		HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Childhood body mass index ( 33045005) Hip circumference adjusted for BMI ( 34021172) Menarche (age at onset) ( 27182965 25231870) Molar-incisor hypomineralization ( 23918034) Response to statin therapy ( 20339536) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking status (ever vs never smokers) ( 30643258) Triglycerides ( 30275531)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		5 interacting genes: FANCM HSPA13 NR1H2 PFDN1 UBE3A	54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		80010	5201
HPRD ID		09867	05357
Ensembl ID		ENSG00000178966	ENSG00000113068
Uniprot IDs		Q9H9A7	O60925
PDB IDs		3MXN 3NBH 3NBI 4CGY 4CHT 4DAY	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?