PFDN1 and SYNDIG1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		PFDN1	SYNDIG1
Description		prefoldin subunit 1	synapse differentiation inducing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Integral Component Of Plasma Membrane Postsynaptic Density Membrane Synaptic Vesicle Membrane Early Endosome Membrane Dendritic Spine Dendritic Shaft Intracellular Membrane-bounded Organelle Cell Body Excitatory Synapse Postsynaptic Density Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding Glutamate Receptor Binding Protein Homodimerization Activity
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Intracellular Protein Transport Positive Regulation Of Synapse Assembly Synaptic Vesicle Clustering
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	LDL cholesterol levels in HIV infection ( 33109212) Sucrose liking ( 31005972)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	16 interacting genes: AQP6 ELOVL4 FATE1 FFAR2 GPR42 GPRC5D LEPROTL1 MAL MFSD6 PFDN1 SLC16A13 SLC35C2 SLC41A1 TLCD4 TMEM43 UNC93B1
Entrez ID		5201	79953
HPRD ID		05357	12766
Ensembl ID		ENSG00000113068	ENSG00000101463
Uniprot IDs		O60925	Q9H7V2
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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