MCM4 and SSRP1

Number of citations of the paper that reports this interaction (PubMedID 16902406)
81

Data Source:
HPRD (in vivo)

		MCM4	SSRP1
Description		minichromosome maintenance complex component 4	structure specific recognition protein 1
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Membrane MCM Complex CMG Complex	Nucleoplasm Nucleolus FACT Complex
	Molecular Function	DNA Helicase Activity Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Unwinding Involved In DNA Replication DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation	DNA Replication DNA Repair Regulation Of Chromatin Organization
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494)
Interacting Genes		27 interacting genes: CCNA1 CDC5L CDC7 CDK1 CDK2 CDT1 DBF4 EP300 ESCO2 LIG4 MCM2 MCM3 MCM6 MCM7 MCM8 MCMBP ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 RPA1 SSRP1 SUMO2 SUPT16H TLX2	20 interacting genes: AURKA CHD1 CHMP1B CSNK2A1 DHX9 EXOSC10 H2AC20 H2BC21 H3-3A MCM4 MYCBP NEK9 PTEN RAN ROBO2 SPI1 SREK1 SRF SUMO2 UBE2I
Entrez ID		4173	6749
HPRD ID		09094	05061
Ensembl ID		ENSG00000104738	ENSG00000149136
Uniprot IDs		B3KMX0 B4DLA6 P33991	A0A024R4Z6 Q08945
PDB IDs		6XTX 6XTY	4IFS 5UMR 5UMS 5VWE 6L1E 6L1R 6L34 6UPK 6UPL
Enriched GO Terms of Interacting Partners?
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