IWS1 and SAP130

		IWS1	SAP130
Description		interacts with SUPT6H, CTD assembly factor 1	Sin3A associated protein 130
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Speck Sin3-type Complex
	Molecular Function	Protein Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085)	Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		11 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A SAP130 STAT2 SUPT6H TCEA1	12 interacting genes: ARID4B CCR9 CUL2 GPS1 IWS1 MARCO MECOM MYC NIFK SFT2D3 SGK2 SMAD3
Entrez ID		55677	79595
HPRD ID		07639	18015
Ensembl ID		ENSG00000163166	ENSG00000136715
Uniprot IDs		Q96ST2	A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3
PDB IDs		6EMR
Enriched GO Terms of Interacting Partners?
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