IWS1 and SUPT6H

Number of citations of the paper that reports this interaction (PubMedID 19141475)
114

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IWS1	SUPT6H
Description		interacts with SUPT6H, CTD assembly factor 1	SPT6 homolog, histone chaperone and transcription elongation factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation	Blastocyst Formation Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085)	Pulse pressure ( 30578418)
Interacting Genes		11 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A SAP130 STAT2 SUPT6H TCEA1	13 interacting genes: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2
Entrez ID		55677	6830
HPRD ID		07639	03211
Ensembl ID		ENSG00000163166	ENSG00000109111
Uniprot IDs		Q96ST2	Q7KZ85
PDB IDs		6EMR	6GME 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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