DHX58 and STAU2

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (pull down)

		DHX58	STAU2
Description		DExH-box helicase 58	staufen double-stranded RNA binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleolus Endoplasmic Reticulum Microtubule Membrane
	Molecular Function	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding ATP Hydrolysis Activity	RNA Binding Double-stranded RNA Binding Protein Binding
	Biological Process	Response To Virus Response To Bacterium Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)	Alzheimer's disease (late onset) ( 30820047) Axial length ( 24144296) Body shape index ( 34021172) Malaria ( 31844061) Pelvic organ prolapse (moderate/severe) ( 26545240) Refractive error ( 32231278) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2 TRIM14	3 interacting genes: CEP126 DHX58 OGT
Entrez ID		79132	27067
HPRD ID		13115	09328
Ensembl ID		ENSG00000108771	ENSG00000040341
Uniprot IDs		A0A024R1Y5 Q96C10	A8K276 Q4LE57 Q9NUL3
PDB IDs		2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?
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