DHX58

Description		DExH-box helicase 58
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding ATP Hydrolysis Activity
	Biological Process	Response To Virus Response To Bacterium Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2 TRIM14
Entrez ID		79132
HPRD ID		13115
Ensembl ID		ENSG00000108771
Uniprot IDs		A0A024R1Y5 Q96C10
PDB IDs		2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?
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