STAU2 and DHX58

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (pull down)

		STAU2	DHX58
Description		staufen double-stranded RNA binding protein 2	DExH-box helicase 58
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Endoplasmic Reticulum Microtubule Membrane	Cytoplasm
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding ATP Hydrolysis Activity
	Biological Process		Response To Virus Response To Bacterium Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways			DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Axial length ( 24144296) Body shape index ( 34021172) Malaria ( 31844061) Pelvic organ prolapse (moderate/severe) ( 26545240) Refractive error ( 32231278) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 34021172)	Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		3 interacting genes: CEP126 DHX58 OGT	10 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2 TRIM14
Entrez ID		27067	79132
HPRD ID		09328	13115
Ensembl ID		ENSG00000040341	ENSG00000108771
Uniprot IDs		A8K276 Q4LE57 Q9NUL3	A0A024R1Y5 Q96C10
PDB IDs			2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?
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