DHX58 and NKRF

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (pull down)

		DHX58	NKRF
Description		DExH-box helicase 58	NFKB repressing factor
Image
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding ATP Hydrolysis Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific RNA Binding Protein Binding
	Biological Process	Response To Virus Response To Bacterium Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway	Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2 TRIM14	13 interacting genes: ADARB1 DHX15 DHX58 HMOX2 KIFC1 NFKB1 NFKB2 PRKN PRKRA REL RELA STAU1 ZNF346
Entrez ID		79132	55922
HPRD ID		13115	02341
Ensembl ID		ENSG00000108771	ENSG00000186416
Uniprot IDs		A0A024R1Y5 Q96C10	A3F769 O15226
PDB IDs		2RQA 2W4R 3EQT	6SH6 6SH7
Enriched GO Terms of Interacting Partners?
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