VKORC1 and SLC31A2

Number of citations of the paper that reports this interaction (PubMedID 21103663)
9

Data Source:
BioGRID (two hybrid)

		VKORC1	SLC31A2
Description		vitamin K epoxide reductase complex subunit 1	solute carrier family 31 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome
	Molecular Function	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding	Copper Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Xenobiotic Metabolic Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation Vitamin K Metabolic Process Bone Development	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport
Pathways		Metabolism of vitamin K
Drugs		Menadione Dicoumarol Phenindione Warfarin Phenprocoumon Acenocoumarol
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Warfarin maintenance dose ( 18535201 20833655 19300499 26265036) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		94 interacting genes: AHSG APLP2 APOA1 APOA2 APOC1 APOC3 APOC4 ARL6IP5 ASGR1 ASGR2 ATP5MC3 ATP6AP2 BCAP31 C1S CCDC12 CCDC167 CD63 CD81 CD9 CLDN10 CNN3 COMT CPLX4 CREB3 CREB3L1 CXADR DCTPP1 DPM2 ECHDC1 FAM209A FAM210B FGG FGL1 FIS1 FTL GJB1 GORAB GPR152 HAMP HDAC6 HOMER2 HP HPR HSD17B7 IFITM3 JAGN1 KCNK17 LIG4 LMNA MANBAL METTL7B MSMO1 MSRB1 MT1X MUC1 PCDH1 PCMT1 PDIA6 PIGH PLP2 PPA2 PPIB PROCR REEP5 RMDN1 RMDN3 RMND5A SAA1 SAT1 SERPINA1 SLC15A3 SLC22A2 SLC25A1 SLC31A2 SLC7A14 SNORA12 SPTSSA STAT6 SURF4 TF TMBIM4 TMEM120A TMEM134 TMEM176A TMEM230 TMEM242 TMEM256 TMEM35B TMEM45B TRAM1 TREX1 VAPB YIF1A ZCCHC24	9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1
Entrez ID		79001	1318
HPRD ID		10540	04365
Ensembl ID		ENSG00000167397	ENSG00000136867
Uniprot IDs		A0A0S2Z5X7 A0A0S2Z6I4 Q9BQB6	O15432 Q53X94
PDB IDs		6WV3 6WV4 6WV5 6WV6 6WV7 6WVH
Enriched GO Terms of Interacting Partners?
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