VARS1 and EEF1D

Number of citations of the paper that reports this interaction (PubMedID 8294461)
23

Data Source:
HPRD (in vitro)

		VARS1	EEF1D
Description		valyl-tRNA synthetase 1	eukaryotic translation elongation factor 1 delta
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity Protein Binding ATP Binding	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Valyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation
Pathways		Cytosolic tRNA aminoacylation	Eukaryotic Translation Elongation
Drugs		Valine
Diseases
GWAS			Schizophrenia ( 31268507)
Interacting Genes		8 interacting genes: CACNA1A CALCOCO2 CAMK2A CDC42 EEF1D MTNR1A SUMO2 YWHAQ	44 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 LINC01232 MAP1B NR2F1 POT1 PRKCA RELA RNF20 RNF40 RPS6KA1 SIAH1 SIAH2 SLC26A4-AS1 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1
Entrez ID		7407	1936
HPRD ID		10362	00560
Ensembl ID		ENSG00000204394	ENSG00000104529
Uniprot IDs		A0A024RCN6 P26640	B2RAR6 D3DWK1 P29692
PDB IDs			2MVM 2MVN 2N51 5JPO
Enriched GO Terms of Interacting Partners?
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