EEF1D and ATG7

Number of citations of the paper that reports this interaction (PubMedID 20195357)
31

Data Source:
BioGRID (pull down)

		EEF1D	ATG7
Description		eukaryotic translation elongation factor 1 delta	autophagy related 7
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Axon Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Protein Binding Transcription Factor Binding Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation C-terminal Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Aging Cellular Response To Starvation Response To Glucose Positive Regulation Of Autophagy Protein Transport Macroautophagy Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Piecemeal Microautophagy Of The Nucleus Suppression By Virus Of Host Autophagy Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Late Nucleophagy Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Chaperone-mediated Autophagy Cellular Response To Morphine Cellular Response To Hyperoxia Positive Regulation By Symbiont Of Host Autophagy Negative Regulation Of Mitochondrial DNA Replication Response To Fluoride Negative Regulation Of Oxidative Stress-induced Neuron Death
Pathways		Eukaryotic Translation Elongation	Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF1 fusions Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Schizophrenia ( 31268507)	Aspartate aminotransferase levels ( 33547301) Body fat mass ( 28552196) Body size at age 10 ( 32376654) Circulating chemerin levels ( 25521368) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 28869591) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) Relative hand skill in reading disability ( 24068947) Small vessel stroke ( 29123153) Systolic blood pressure ( 27618447 27618452 30578418) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		44 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 LINC01232 MAP1B NR2F1 POT1 PRKCA RELA RNF20 RNF40 RPS6KA1 SIAH1 SIAH2 SLC26A4-AS1 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	10 interacting genes: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B
Entrez ID		1936	10533
HPRD ID		00560	12293
Ensembl ID		ENSG00000104529	ENSG00000197548
Uniprot IDs		B2RAR6 D3DWK1 P29692	B3KQM6 O95352
PDB IDs		2MVM 2MVN 2N51 5JPO
Enriched GO Terms of Interacting Partners?
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