TAL2 and PCBD2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		TAL2	PCBD2
Description		TAL bHLH transcription factor 2	pterin-4 alpha-carbinolamine dehydratase 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin	Cellular_component Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)
Interacting Genes		11 interacting genes: CBFA2T2 CDK6 HLA-DQA1 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4	41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		6887	84105
HPRD ID		01735	17824
Ensembl ID		ENSG00000186051	ENSG00000132570
Uniprot IDs		Q16559	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?
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