PCBD2 and CERS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PCBD2	CERS3
Description		pterin-4 alpha-carbinolamine dehydratase 2	ceramide synthase 3
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated	Epidermis Development Sphingolipid Biosynthetic Process Keratinocyte Differentiation Ceramide Biosynthetic Process Cornification
Pathways			Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)	Childhood body mass index ( 31752434) Cotinine glucuronidation ( 25293881)
Interacting Genes		41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	5 interacting genes: NEU1 ORMDL3 PCBD2 SLC29A2 SLC39A9
Entrez ID		84105	204219
HPRD ID		17824	13961
Ensembl ID		ENSG00000132570	ENSG00000154227
Uniprot IDs		Q9H0N5	Q8IU89
PDB IDs		4C45
Enriched GO Terms of Interacting Partners?
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