PCBD2 and ZZZ3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PCBD2	ZZZ3
Description		pterin-4 alpha-carbinolamine dehydratase 2	zinc finger ZZ-type containing 3
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GO Annotations	Cellular Component	Cellular_component Nucleus	Nucleoplasm Nucleolus
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated	Histone H4 Acetylation
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)	Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body shape index ( 34021172) Height ( 31562340) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Obesity ( 23563607) Platelet count ( 32888494) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	21 interacting genes: BLZF1 CARD9 DNAJB11 EFHC2 EPS8 FAM124A GATA1 GOLGA2 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 PICK1 PPP1R13B TRAF2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513
Entrez ID		84105	26009
HPRD ID		17824	15907
Ensembl ID		ENSG00000132570	ENSG00000036549
Uniprot IDs		Q9H0N5	Q8IYH5
PDB IDs		4C45	2FC7 2YUM 6E83 6E86
Enriched GO Terms of Interacting Partners?
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