STAT1 and IRF2

  • Number of citations of the paper that reports this interaction (PubMedID 15778351)
  • 17
  • Data Source:
  • HPRD (in vitro)

STAT1

IRF2

Description signal transducer and activator of transcription 1 interferon regulatory factor 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute kidney injury in critical illness ( 27576016)
  • Adverse response to drug ( 30420678)
  • Chronic lymphocytic leukemia ( 28165464)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lewy body disease ( 25188341)
  • Night sleep phenotypes ( 27126917)
  • Nonsyndromic cleft lip ( 31609978)
  • Type 1 diabetes ( 34012112)
Interacting Genes 109 interacting genes: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CDC42 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DDX6 DOT1L DUSP2 DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 FADD FANCC FGFR3 FGFR4 FLT1 FOS FTH1 FYN GFAP GTF2I HADH HLA-B HSF1 HSP90AB1 HSPA8 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK MFSD6 MT-ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RACK1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTB SPTBN1 SRC STAT2 STAT3 STAT4 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBE2I VDR XPO1 ZNF467 24 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFE2L2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1 TRIM55 TRIM63
Entrez ID 6772 3660
HPRD ID 02777 00962
Ensembl ID ENSG00000115415 ENSG00000168310
Uniprot IDs P42224 P14316
PDB IDs 1BF5 1YVL 2KA6 3WWT
Enriched GO Terms of Interacting Partners?
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