SLC2A5 and FCRL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC2A5	FCRL3
Description		solute carrier family 2 member 5	Fc receptor like 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Specific Granule Membrane Sarcolemma Extracellular Exosome	Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Fructose Transmembrane Transporter Activity Glucose Transmembrane Transporter Activity Protein Binding Fructose Binding	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Carbohydrate Metabolic Process Response To Fructose Fructose Transmembrane Transport Cellular Response To Fructose Stimulus Intestinal Hexose Absorption Glucose Transmembrane Transport Fructose Import Across Plasma Membrane	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity
Pathways		Neutrophil degranulation Intestinal hexose absorption
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 32912934 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)
Interacting Genes		17 interacting genes: ARL13B ATP6V0B CCL5 COMT EVI2B FCRL3 LMNA MGST3 MTERF3 MTOR PAGE1 RPSA SCN3B SLC45A1 TMEM130 TMEM237 TNFRSF25	12 interacting genes: AGPAT4 CMTM5 FCRL1 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70
Entrez ID		6518	115352
HPRD ID		00690	07352
Ensembl ID		ENSG00000142583	ENSG00000160856
Uniprot IDs		A0A140VJK5 B4DG19 P22732	Q96P31
PDB IDs		1YG1
Enriched GO Terms of Interacting Partners?
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