FCRL3 and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCRL3	CMTM5
Description		Fc receptor like 3	CKLF like MARVEL transmembrane domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface	Extracellular Space Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding	Cytokine Activity Protein Binding
	Biological Process	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 32912934 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)
Interacting Genes		12 interacting genes: AGPAT4 CMTM5 FCRL1 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70	131 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35C2 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		115352	116173
HPRD ID		07352	06986
Ensembl ID		ENSG00000160856	ENSG00000166091
Uniprot IDs		Q96P31	Q96DZ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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