FCRL3 and AGPAT4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCRL3	AGPAT4
Description		Fc receptor like 3	1-acylglycerol-3-phosphate O-acyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Acyltransferase Activity
	Biological Process	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity	Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways			Synthesis of PA
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 32912934 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)	Anxiety in major depressive disorder ( 24047446) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Fear of pain ( 28701861) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: AGPAT4 CMTM5 FCRL1 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70	28 interacting genes: AQP12B AQP6 CNR2 CREB3L1 ERGIC3 FCGR2A FCRL3 FFAR2 GPR101 HSD17B11 HSD17B13 JAGN1 LEPROTL1 LEUTX LRRC25 MFF MFSD14B MGST3 REEP4 REL RETREG3 SCN3B SLC35C2 SLC7A8 SPACA1 TMEM14B TMEM31 TMX2
Entrez ID		115352	56895
HPRD ID		07352	12437
Ensembl ID		ENSG00000160856	ENSG00000026652
Uniprot IDs		Q96P31	Q9NRZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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