SKIV2L and PMPCA

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		SKIV2L	PMPCA
Description		Ski2 like RNA helicase	peptidase, mitochondrial processing subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Ski Complex	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Hydrolase Activity	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay	Protein Processing Involved In Protein Targeting To Mitochondrion
Pathways		Association of TriC/CCT with target proteins during biosynthesis mRNA decay by 3' to 5' exoribonuclease	Mitochondrial protein import Processing of SMDT1
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 23577725 20861866) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite levels ( 24816252) Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Coronary artery disease ( 29212778) Disease progression in age-related macular degeneration ( 29346644) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) vWF levels ( 30586737) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		15 interacting genes: CACNB3 CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA PRKAA2 PRODH RHOU SNRPB TNRC17 TSSK2 WDR1 XRN1	16 interacting genes: ASS1 AVEN BMPR2 KIF2C LINC01554 NDOR1 NPSR1 NSMF OGT OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1 ZNF76
Entrez ID		6499	23203
HPRD ID		02724	07500
Ensembl ID		ENSG00000204351	ENSG00000165688
Uniprot IDs		A0A1U9X8J1 Q15477	Q10713
PDB IDs
Enriched GO Terms of Interacting Partners?
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