PMPCA and UBAC1

		PMPCA	UBAC1
Description		peptidase, mitochondrial processing subunit alpha	UBA domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion	Protein Ubiquitination
Pathways		Mitochondrial protein import Processing of SMDT1	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		16 interacting genes: ASS1 AVEN BMPR2 KIF2C LINC01554 NDOR1 NPSR1 NSMF OGT OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1 ZNF76	36 interacting genes: AIRE APP ARRDC3 CARD14 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 PMPCA POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B
Entrez ID		23203	10422
HPRD ID		07500	12170
Ensembl ID		ENSG00000165688	ENSG00000130560
Uniprot IDs		Q10713	A0A140VK64 Q9BSL1
PDB IDs			2DAI
Enriched GO Terms of Interacting Partners?
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