PMPCA and SKIV2L

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		PMPCA	SKIV2L
Description		peptidase, mitochondrial processing subunit alpha	Ski2 like RNA helicase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleus Cytosol Ski Complex
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Hydrolase Activity
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion	RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay
Pathways		Mitochondrial protein import Processing of SMDT1	Association of TriC/CCT with target proteins during biosynthesis mRNA decay by 3' to 5' exoribonuclease
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 23577725 20861866) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite levels ( 24816252) Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Coronary artery disease ( 29212778) Disease progression in age-related macular degeneration ( 29346644) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) vWF levels ( 30586737) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		16 interacting genes: ASS1 AVEN BMPR2 KIF2C LINC01554 NDOR1 NPSR1 NSMF OGT OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1 ZNF76	15 interacting genes: CACNB3 CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA PRKAA2 PRODH RHOU SNRPB TNRC17 TSSK2 WDR1 XRN1
Entrez ID		23203	6499
HPRD ID		07500	02724
Ensembl ID		ENSG00000165688	ENSG00000204351
Uniprot IDs		Q10713	A0A1U9X8J1 Q15477
PDB IDs
Enriched GO Terms of Interacting Partners?
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