ST3GAL3 and KCNQ4

		ST3GAL3	KCNQ4
Description		ST3 beta-galactoside alpha-2,3-sialyltransferase 3	potassium voltage-gated channel subfamily Q member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Basal Plasma Membrane Integral Component Of Membrane
	Molecular Function	Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Protein Glycosylation Oligosaccharide Biosynthetic Process Ganglioside Biosynthetic Process Via Lactosylceramide O-glycan Processing Keratan Sulfate Biosynthetic Process Viral Protein Processing Sialylation	Potassium Ion Transport Sensory Perception Of Sound Regulation Of Ion Transmembrane Transport Inner Ear Morphogenesis Potassium Ion Transmembrane Transport
Pathways		Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis	Voltage gated Potassium channels Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs			Enflurane Promethazine Miconazole Ezogabine ICA-105665
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256) Serum alkaline phosphatase levels ( 33547301)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		19 interacting genes: ACTG1 CAVIN2 EIF2B3 FBLN5 HDAC5 KCNQ4 KDM4A LASP1 MOB3B NASP PIK3R3 POU3F1 RPL8 RRM2 SCAMP2 TGFB1I1 TTR VTI1A ZBTB5	2 interacting genes: KCNQ3 ST3GAL3
Entrez ID		6487	9132
HPRD ID		05930	04641
Ensembl ID		ENSG00000126091	ENSG00000117013
Uniprot IDs		A0A2R8Y732 Q11203	B3KQH8 P56696
PDB IDs			2OVC 4GOW 6N5W 7BYL 7BYM 7BYN
Enriched GO Terms of Interacting Partners?
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