RPGR and SMC1A

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		RPGR	SMC1A
Description		retinitis pigmentosa GTPase regulator	structural maintenance of chromosomes 1A
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Mitotic Spindle Pole
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	DNA Binding Chromatin Binding RNA Binding Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	Mitotic Sister Chromatid Segregation DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Response To Radiation Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Response To DNA Damage Checkpoint Signaling Mitotic Spindle Assembly
Pathways			Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Mean corpuscular volume ( 32888494)
Interacting Genes		19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE	21 interacting genes: ALK AMOT ATM BLM BRCA1 ESR1 FGF14 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3 SUMO2
Entrez ID		6103	8243
HPRD ID		02425	02077
Ensembl ID		ENSG00000156313	ENSG00000072501
Uniprot IDs		Q92834	A0A384MR33 G8JLG1 Q14683 Q68EN4
PDB IDs		4JHN 4JHP 4QAM	6WG3 6WG4 6WG6 6WGE
Enriched GO Terms of Interacting Partners?
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