ELAC2 and CTBP1

Number of citations of the paper that reports this interaction (PubMedID 9858600)
60

Data Source:
HPRD (in vivo)

		ELAC2	CTBP1
Description		elaC ribonuclease Z 2	C-terminal binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Nucleus Nucleoplasm Transcription Repressor Complex Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	RNA Binding Endoribonuclease Activity TRNA-specific Ribonuclease Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding	Transcription Corepressor Binding Chromatin Binding Transcription Corepressor Activity Protein Binding Protein C-terminus Binding Transcription Factor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Domain Specific Binding Identical Protein Binding NAD Binding DNA-binding Transcription Factor Binding
	Biological Process	TRNA Catabolic Process TRNA 3'-end Processing Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Mitochondrial TRNA Processing	Negative Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Negative Regulation Of Cell Population Proliferation Viral Genome Replication Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated White Fat Cell Differentiation Regulation Of Cell Cycle Negative Regulation Of Histone H4 Acetylation
Pathways		tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis	Deactivation of the beta-catenin transactivating complex SUMOylation of transcription cofactors Repression of WNT target genes Signaling by TCF7L2 mutants
Drugs			Formic acid
Diseases
GWAS		Squamous cell lung carcinoma ( 28604730)	Type 2 diabetes ( 31118516 32499647)
Interacting Genes		11 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 DRC3 GID4 GOLM1 NDUFA7 RING1 SMAD2 SUMO2	91 interacting genes: ACTL6B AKAP9 APC ARNT2 ATXN1L BCAS3 BCL3 BMPR2 BRCA1 CBX4 CDC23 CDKN2D CEP68 CHD3 CREBBP CRY2 CTBP2 CTNNA1 DGCR6 DMRTB1 EEF1D ELAC2 ELK3 EP300 FANCC FANCF FANCG FANCL FOXP1 FOXP2 FUNDC1 GTF2B H3-4 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC9 HEMGN HIC1 HOXB5 HTT IKZF1 IKZF2 KAT2B KDM1A KLF12 KLF3 LNX1 MAML2 MAPK9 MARCHF10 MECOM NME2 NOL4 NOL4L NOS1 NRIP1 NTAQ1 ORC4 PIAS2 PLCB1 PNN PRKAA1 PRKCI RAI2 RB1 RBBP5 RBBP8 RBM14 RCOR1 RNF111 SIN3A SNRPN SOBP SPEN TBP TCF4 TEAD4 TERF2 TERF2IP TGIF1 THAP11 TSHZ3 ZBP1 ZBTB18 ZEB1 ZEB2 ZFPM2 ZNF219
Entrez ID		60528	1487
HPRD ID		05641	04015
Ensembl ID		ENSG00000006744	ENSG00000159692
Uniprot IDs		A0A0S2Z5M8 Q9BQ52	Q13363 X5D8Y5
PDB IDs			1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR 6V89 6V8A 7KWM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?