ELAC2 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ELAC2	ASCC2
Description		elaC ribonuclease Z 2	activating signal cointegrator 1 complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	RNA Binding Endoribonuclease Activity TRNA-specific Ribonuclease Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding	Protein Binding Ubiquitin Binding
	Biological Process	TRNA Catabolic Process TRNA 3'-end Processing Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Mitochondrial TRNA Processing	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Squamous cell lung carcinoma ( 28604730)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		11 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 DRC3 GID4 GOLM1 NDUFA7 RING1 SMAD2 SUMO2	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		60528	84164
HPRD ID		05641	16515
Ensembl ID		ENSG00000006744	ENSG00000100325
Uniprot IDs		A0A0S2Z5M8 Q9BQ52	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs			2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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