RABGGTB and RAB37

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RABGGTB	RAB37
Description		Rab geranylgeranyltransferase subunit beta	RAB37, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Endosome Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Azurophil Granule Membrane Specific Granule Membrane
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Prenylation Protein Geranylgeranylation	Protein Transport
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation	Neutrophil degranulation RAB geranylgeranylation
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422) Granulocyte count ( 27863252) Liver fibrosis in pediatric non-alcoholic fatty acid liver disease ( 28918882) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neurological blood protein biomarker levels ( 31320639) Neutrophil count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		21 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA RPS6KA1 SH3GLB1 TAFA1 TMEM25 WDR4	5 interacting genes: EWSR1 MAL2 RAB5A RABGGTB RIMS1
Entrez ID		5876	326624
HPRD ID		01532	06702
Ensembl ID		ENSG00000137955	ENSG00000172794
Uniprot IDs		A8KAJ2 P53611 Q6IB63	A0A024R8K6 B3KPZ5 B7Z3L0 Q96AX2
PDB IDs		6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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