RAB37 and RABGGTB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RAB37	RABGGTB
Description		RAB37, member RAS oncogene family	Rab geranylgeranyltransferase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Azurophil Granule Membrane Specific Granule Membrane	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Protein Transport	Cellular Protein Modification Process Visual Perception Protein Prenylation Protein Geranylgeranylation
Pathways		Neutrophil degranulation RAB geranylgeranylation	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs			N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422) Granulocyte count ( 27863252) Liver fibrosis in pediatric non-alcoholic fatty acid liver disease ( 28918882) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neurological blood protein biomarker levels ( 31320639) Neutrophil count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		5 interacting genes: EWSR1 MAL2 RAB5A RABGGTB RIMS1	21 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA RPS6KA1 SH3GLB1 TAFA1 TMEM25 WDR4
Entrez ID		326624	5876
HPRD ID		06702	01532
Ensembl ID		ENSG00000172794	ENSG00000137955
Uniprot IDs		A0A024R8K6 B3KPZ5 B7Z3L0 Q96AX2	A8KAJ2 P53611 Q6IB63
PDB IDs			6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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