RABGGTB and B4GALT7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RABGGTB	B4GALT7
Description		Rab geranylgeranyltransferase subunit beta	beta-1,4-galactosyltransferase 7
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Protein Binding Galactosyltransferase Activity Manganese Ion Binding Xylosylprotein 4-beta-galactosyltransferase Activity
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Prenylation Protein Geranylgeranylation	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Proteoglycan Metabolic Process Cellular Protein Modification Process Protein N-linked Glycosylation Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Negative Regulation Of Fibroblast Proliferation Glycosylation Supramolecular Fiber Organization
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation	A tetrasaccharide linker sequence is required for GAG synthesis Defective B4GALT7 causes EDS, progeroid type
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	Blood protein levels ( 30072576) Methadone dose in opioid dependence ( 28115739) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA RPS6KA1 SH3GLB1 TAFA1 TMEM25 WDR4	7 interacting genes: CYSRT1 KRT31 KRTAP10-3 KRTAP10-7 PBRM1 RABGGTB TMEM14B
Entrez ID		5876	11285
HPRD ID		01532	05060
Ensembl ID		ENSG00000137955	ENSG00000027847
Uniprot IDs		A8KAJ2 P53611 Q6IB63	B3KMT1 Q9UBV7
PDB IDs		6J6X 6J74 6J7F 6J7X 6O60	4IRP 4IRQ
Enriched GO Terms of Interacting Partners?
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